Kungani Sidinga Imithi Esebenzayo?

• Umphakathi wethu ubhekene nokwanda okukhulu kwenani labantu abahlushwa izifo eziyinkimbinkimbi, ezingapheli�ezifana nesifo sikashukela, isifo senhliziyo, umdlavuza, ukugula ngengqondo, kanye nokuphazamiseka kwe-autoimmune njenge-rheumatoid arthritis.
• Uhlelo lwezokwelapha olusetshenziswa odokotela abaningi lugxile ekunakekelweni okubuhlungu,�ukuxilongwa nokwelashwa kokuhlukumezeka noma ukugula okwesikhathi esifushane futhi okudinga ukunakekelwa okuphuthumayo, njenge-appendicitis noma umlenze ophukile. Odokotela basebenzisa izindlela zokwelapha eziqondile, ezinqunyiwe njengezidakamizwa noma ukuhlinza okuhloswe ngayo ukwelapha inkinga esheshayo noma uphawu.
• Ngeshwa, indlela yokunakekela kakhulu emithini ayinayo indlela efanele namathuluzi okuvimbela nokwelapha izifo eziyinkimbinkimbi, ezingalapheki.�Ezimweni eziningi akunaki ukwakheka kofuzo okuyingqayizivele komuntu ngamunye noma izici ezifana nokuchayeka kwemvelo ebuthini nezici zendlela yokuphila yanamuhla ezinethonya eliqondile ekwandeni kwezifo ezingelapheki emphakathini wanamuhla waseNtshonalanga.
• Kunegebe elikhulu phakathi kocwaningo kanye nendlela odokotela abasebenza ngayo.�Igebe phakathi kocwaningo olusafufusa lwesayensi eyisisekelo kanye nokuhlanganiswa emsebenzini wezokwelapha likhulu �iminyaka engama-50�ikakhulukazi endaweni yokugula okuyinkimbinkimbi, okungamahlalakhona.
• Odokotela abaningi abaqeqeshiwe ngokwanele ukuze bahlole izimbangela eziwumsuka�yezifo eziyinkimbinkimbi, ezingalapheki nokusebenzisa amasu afana nokudla, ukudla, nokuzivocavoca kukho kokubili ukwelapha nokuvimbela lezi zifo ezigulini zabo.

Ihluke Kanjani Imithi Esebenzayo?

Umuthi osebenzayo ubandakanya�ukuqonda�umsuka, ukuvimbela, kanye nokwelashwa�yesifo esiyinkimbinkimbi, esingamahlalakhona. Izimpawu zendlela yokwelapha esebenzayo zihlanganisa:

• Ukunakekelwa okugxiliswe esigulini.�Ukugxila komuthi osebenzayo kusekunakekelweni okugxile esigulini, ukukhuthaza impilo njengokuqina okuhle, okungaphezu nje kokungabikho kwezifo. Ngokulalela isiguli nokufunda indaba yaso, udokotela uletha isiguli enqubweni yokutholwa futhi athunge izindlela zokwelapha ezibhekana nezidingo ezihlukile zomuntu ngamunye.
• Indlela yokunakekelwa kwezempilo edidiyelwe, esekwe kwisayensi.�Abasebenzi bezokwelapha abasebenzayo babheka �umfula� ukuze bacabangele iwebhu eyinkimbinkimbi yokusebenzisana emlandweni wesiguli, iphysiology, nendlela yokuphila engaholela ekuguleni. Kucatshangelwa ukwakheka kofuzo okuyingqayizivele kwesiguli ngasinye, kanye nakho kokubili kwangaphakathi (ingqondo, umzimba, nomoya) kanye nezici zangaphandle (indawo engokwenyama nengokwenhlalo) ezithinta ukusebenza okuphelele.
• Ukuhlanganisa izindlela zokwelapha ezihamba phambili.�Umuthi osebenzayo uhlanganisa izindlela zokwelapha zaseNtshonalanga nalokho ngezinye izikhathi okubhekwa enye indlela noma umuthi ohlanganisayo , kudala ukugxila ekuvimbeleni ngokudla okunempilo, ukudla, nokuzivocavoca; ukusetshenziswa kokuhlolwa kwelabhorethri kwakamuva kanye nezinye izindlela zokuxilonga; nezinhlanganisela ezinqunyiwe zezidakamizwa kanye/noma imithi yezitshalo, izithasiselo, ukudla okwelaphayo, izinhlelo zokuqeda ubuthi, noma amasu okulawula ingcindezi.

Umuthi osebenzayo ungaphezu kwendlela ehlukile ekunakekelweni kwezempilo, kuyifilosofi ehluke ngokuphelele mayelana nokuthi sobabili sihlinzeka futhi sikudla kanjani ukunakekelwa kwezempilo.� Ngingasho ngobuqotho ukuthi ekusebenzeni kwami, angilaphi izifo, kodwa kunalokho ngelaphe iziguli; abanye abanezifo kanti abanye abanazo.� Ngigxila ekuguquleni umzimba ngendlela ejwayelekile kanye nokubuyisela ukusebenza okunempilo ngokudla okunempilo nokushintsha indlela yokuphila.

Abantu bavame ukuba nezimpawu eziphawulekayo futhi bazizwe begula, kodwa abahlangabezani nezidingo zobuchwepheshe zokuxilongwa okuthile.� Emahhovisi amaningi lokhu kusho ukuthi abatholi nhlobo ukwelashwa, kodwa ezigulini zami, lokhu kumane nje kuwukwelashwa. ukuqala.� Ngisebenza neziguli zami ukuthola amaphethini angasebenzi aholela ezimpawini zazo, bese ngithuthukisa amasu okulungisa lawa maphethini kanye nokubuyisela impilo engcono. �

Indlela yokwelapha esebenzayo ekwelapheni isifo esingamahlalakhona yileyo engasekelwe ku-ejenti eyodwa noma indlela ethile njengesixazululo sokwelapha noma sokuphulukisa. Kugxilwe ngokuphelele esimisweni sokuthi ukubuyiselwa kwe-metabolism efanele yamangqamuzana, ngokunciphisa umthwalo onobuthi okhulayo kanye nokucindezeleka okwenziwe nge-oxidative emzimbeni, kuzovumela ukuphefumula kwe-mitochondrial, ukukhiqizwa kwamandla eselula, futhi ekugcineni kuncishiswe izimpawu nezimpawu zesifo esingamahlalakhona. . Nakuba odokotela abaningi abagxile ekudleni okunomsoco bebona ukuthi izimiso ezijwayelekile zokwesekwa kokudla okunomsoco zizodwa zinenzuzo enkulu ezimweni zesifo esingelapheki esimaphakathi kuya kwesisesilinganisweni, izimo ezinzima kakhulu ngokuvamile zidinga indlela yokusebenza ebanzi.

Le filosofi yemithi esebenzayo kanye nendlela yaqala ukuthuthukiswa ukuze isetshenziswe emtholampilo ezigulini zokukhathala okungapheli ezinemiphumela emihle kakhulu, futhi ngenxa yokufana okubonwa ezimweni eziningi ezingapheli, iye yasetshenziswa phakathi neminyaka kwezinye izifo ngempumelelo enkulu, kuhlanganise ne-fibromyalgia, i-rheumatoid arthritis. , kanye nokuphazamiseka kwe-auto-immune.^1-8 Umsebenzi we-seminal ka-Bland, u-Rigden, u-Cheney, nabanye ekwelapheni isifo sokukhathala okungapheli uye wasebenza njengesifanekiso esiphumelelayo, futhi le ndlela manje isetshenziselwa ukwelapha uhla olubanzi lwezifo ezingapheli.^1-7.

Ifilosofi yemithi esebenzayo igxile esisekelweni sokuthi ukuwohloka kwe-mucosa yamathumbu ngokungenwa okungapheli kokudla kanye nobuthi obusekelwe emanzini, kanye nokusetshenziswa kwezidakamizwa ezivamile kanye nezidakamizwa ezithengiswa kakhulu (njengama-antibiotics kanye ne-NSAIDS), kuholela ku-dysbiosis kanye ne-hyperpermeable mucosa yamathumbu, noma i-leaky gut syndrome. Lokhu hyperpermeablity yamathumbu kungabangela ukuthi i-mucosa yamathumbu ihluleke ukusebenza njengesithiyo esikhethiwe, okuholela ekuweleni kobuthi obusekelwe ekudleni kanye namaprotheni okudla okugaywe kancane ngokusebenzisa i-mucosa yamathumbu kanye nokungena kwegazi okuhlelekile. Umphumela uba ukwanda kokungezwani nokudla kanye nokwanda komthwalo onobuthi. (bheka Umfanekiso 1).

Lokhu kwanda komthwalo onobuthi, ngokuhamba kwesikhathi, kungaholela ekucindezelekeni okwandayo esibindini kanye nekhono laso lokuqeda ngokwanele lezi zinto ngokusebenzisa izindlela zesigaba I no-II. Lokhu ekugcineni kuzoholela ekwandeni kobuthi bezicubu zesistimu.

Ukwanda kobuthi kwezicubu kucatshangwa ukuthi kuyimbangela enkulu yokungasebenzi kahle kwe-mitochondrial, okuholela ekungakwazini kwamangqamuzana omzimba, okuhlanganisa namaseli emisipha, ukusebenzisa kahle izindlela ezincike kumoya-mpilo we-aerobic metabolism. Lokhu kubala ukukhiqiza okuningi kwe-ATP. Ukuncipha kokukhiqizwa kwe-ATP yamaselula kungalandisa ngezimpawu eziningi (uma kungezona zonke) zezimpawu ezihambisana nezimo eziningi zezifo ezingamahlalakhona, njenge-chronic fatigue syndrome (CFS) kanye ne-fibromyalgia (FMS).

Ukwanda kokungena kwamathumbu emathunjini kungase futhi kubangele amaprotheni okudla agayiwe kancane kuya kwamakhulu angena egazini futhi asebenze njengama-antigen. Imiphumela ye-antigen-antibody complexes ibonakala inobudlelwane be-synovium ye-articulations, Lokhu kubangela impendulo yokuvuvukala emigqeni ehlangene evame ukubonakala ku-arthritidies njenge-rheumatoid arthritis (RA). Imithi yokwelapha eyinhloko esetshenziswa ekuqaleni ngodokotela abajwayelekile bezokwelapha ekwelapheni i-RA (okuxakayo) ama-NSAID. Ama-NSAID, ngokusho kwe-PDR, abangela ukwanda kwamathumbu emathunjini. Kungenzeka yini ukuthi ukwelashwa okungokwesiko kwe-allopathic kwe-arthritidies kuye kwaphumela kuphela ekudambiseni izimpawu zesiguli, kuyilapho empeleni kubhebhethekisa lesi sifo?

Ngakho-ke, isu elisebenzayo lokwelapha imithi ligxile ekulungiseni i-mucosa yamathumbu, ukulungisa noma yikuphi i-dysbiosis yamathumbu, ukuhlinzeka ngezinto emzimbeni ukuze kusize ukuxoshwa kwezicubu, ukunciphisa ukucindezeleka kwe-oxidative, futhi ekugcineni kukhuthaze ukubuya kwe-metabolism evamile yamaselula. Ukuhlola kuqala ngokunquma impilo yamathumbu kanye nokugcinwa kokusebenza kwesibindi kanye nekhono laso lokususa ubuthi. Lokhu kuvame ukwenziwa ngosizo lwemibuzo yezimpawu zesiguli, njengohlu lwemibuzo lokuhlolwa kwe-metabolic kanye nezifundo zaselabhorethri ezisebenzayo, njengenselelo ye-lactulose/mannitol yokuhlola ukuvunyela kwamathumbu, kanye nokuhlaziywa okuphelele kwendle yokugaya (CDSA) ukuze kutholwe izimpawu zokugaya ukudla. , ukumuncwa, kanye nezitshalo zamakholoni. Amandla okukhipha ubuthi esibindini angahlolwa ngokusebenzisa i-caffeine clearance kanye nokuhlolwa kwenselele ye-metabolite conjugation, ehlola isigaba I (cytochrome P450) kanye nesigaba II (conjugation) izindlela zokususa ubuthi esibindini.bheka Umfanekiso 2). Lokhu kuhlola akwenziwa amalabhorethri omtholampilo ajwayelekile, kodwa kutholakala ngamalabhorethri akhethekile ahlinzeka ngokuhlolwa kokusebenza.⁹

Uma idatha isiqoqiwe, uhlelo lokwelapha (bheka Umfanekiso 3) kukhethwa, okungase kuhlanganise imisoco ethile yokulungisa noma yikuphi ukungasebenzi kahle kwamathumbu (leaky gut syndrome). Izakhi zomuntu ngamunye ezifana ne-L-glutamine, amaprotheni erayisi e-hypoallergenic ahlanzekile, i-inulin, i-pantothenic acid, kanye nama-antioxidants angasetshenziswa, noma kunjalo, ukudla okwenziwa ngefomula.^10,11 ngokuvamile kulula kakhulu futhi kulula ukuyisebenzisa emtholampilo. Ubunzima bokugaya nokumuncwa okuphakanyiswe ku-CDSA bungaphathwa ngokusetshenziswa kwesikhashana kwama-enzyme e-pancreatic kanye ne-HCL (uma kubonisiwe) ezigulini ezingenayo i-gastritis noma izilonda. I-Dysbiosis, igama elisetshenziselwa ukuchaza ukungalingani kwezitshalo ze-colon, ingabhekwa ngokuphathwa kwe-lactobacillus acidophilus nama-probiotics afana ne-fructooligosaccharides (FOS).

Noma yimaphi amagciwane e-pathogenic, imvubelo, noma izimuncagazi ezitholwe ku-CDSA kufanele zelashwe ngemithi (noma yemvelo) ephakanyiswe ukuhlolwa kokuzwela ku-CDSA. Lokhu kungase kuhlanganise izinto ezingagunyaziwe njenge-berberine, i-garlic, i-citrus seed extract, i-artemisia, i-uva ursi, nezinye. Lolu hlelo lokubuyisela amathumbu luchazwa u-Bland, u-Rigden, u-Cheney, nabanye njengendlela ye-“Four R'.^3-4.

“Four R” Indlela Yokubuyisela Amathumbu

Susa: Qeda noma iyiphi i-microflora ye-pathogenic, imvubelo kanye/noma ama-parasite ngama-ejenti emvelo noma kadokotela aphakanyiswe ku-CDSA (okungukuthi, i-berberine/goldenseal, i-garlic, i-artemesia, i-citrus seed extract, i-uva ursi, njll.).

Susa ukudla okwaziwayo okungezwani nomzimba kanye/noma ulandele ukudla okulungisiwe okususayo ngokugwema ukudla okuqukethe i-gluten, futhi ugcizelele ukudla okusha okungacutshunguliwe.

Faka esikhundleni: Nikeza ama-enzyme e-pancreatic multidigestive kanye ne-HCL uma kufanele, ikakhulukazi uma izimpawu ze-malabsorption zikhona ku-CDSA.

Hlanza kabusha: Phatha i-lactobacillus acidophilus, i-bifidobacteria nama-probiotics afana ne-fructooligosaccharides (FOS) ne-inulin.

Ukulungisa: Nikeza izakhi zokusekela ubuqotho be-mucosal yamathumbu, njenge-L-glutamine, i-antioxidants, i-glutathione, i-N-acetylcysteine ​​(NAC), i-zinc, i-pantothenic acid, i-medium chain triglycerides (MCTs), i-fiber, njll.

Ngemuva kokuthi izinkinga zamathumbu zilungiswe ngokuphumelelayo, ukulawulwa kwezindlela zokuqeda isibindi kungafezwa ngokunikeza izakhi ezisetshenziswa esigabeni I biotransformation kanye nesigaba II izindlela zokuhlanganisa. Lokhu kungase kuhlanganise izakhi zomuntu ngamunye ezifana ne-N-acetyl cysteine, i-methionine, i-cysteine, i-glycine, i-glutamic acid, i-glutathione kanye nezakhi ze-antioxidant (bheka Umfanekiso 3). Kodwa-ke, ukusetshenziswa komkhiqizo wokudla owenziwe ngefomula oklanywe ngokukhethekile kuwusizo kakhulu futhi kusebenza kahle kakhulu ukusetshenzwa emtholampilo.

Iziguli ezinomsebenzi we-enzyme we-cytochrome P450 wesigaba esiphakanyisiwe kanye nomsebenzi wokuhlanganisa wesigaba sesi-II esinensayo kufanele zelashwe nge-antioxidant therapy ngaphambi kokuba kuqale ukuqeda ubuthi. Lokhu kunciphisa ukukhiqizwa kwama-molecule aphakathi nendawo anobuthi be-biotransformed okwandisa ingcindezi ye-oxidative emzimbeni.

Konke lokhu kufanele kuhlanganiswe nokudla okugcizelela ukudla okusha, futhi kuqede ukudla okugayiwe kanye nokungezwani komzimba. Lokhu kuzonciphisa iziguli umthwalo onobuthi wokudla (ama-exotoxins), kanti uhlelo lwamathumbu luzonciphisa ubuthi obutholakala emathunjini (endotoxins). Ukulandela ukudla okuguquliwe kokuqeda okuqeda ukungeniswa kwe-gluten kanye nobisi oluqukethe ukudla, nokuyeka izidakamizwa eziningi ngangokunokwenzeka, kuzosiza futhi ngesikhathi senqubo yokukhipha ubuthi.

Okubhekwayo

1. I-Bland J, i-Bralley A: Ukulawulwa komsoco wama-enzyme e-hepatic detoxification, I-J Appl Nutr 44, 1992.
2. Rigden S: Ucwaningo locwaningo-CFIDS umbiko wokuqala wocwaningo: Intuthuko ekuxilongweni nasekwelapheni kwabagula okungalapheki, 1991, Seattle.
3. Rigden S: Uhlelo lwe-Enterohepatic resuscitation lwe-CFIDS, CFIDS IziKr Spring, 1995.
4. I-Cheney PR, i-Lapp CW: Ukuvuselelwa kwe-Entero-hepatic ezigulini ezine-syndrome yokukhathala okungapheli: Iphiramidi yokwelapha okunomsoco, CFIDS IziKr Ngo-1993.
5. I-Lanfranchi RG, et al: I-Fibromyalgia, ubuhlungu obungapheli kanye ne-leaky gut syndrome. I-Chiropr yanamuhla, March/April:32-9, 1994.
6. I-Rowe AH: Ukukhathala okuguquguqukayo kanye ne-toxemia, U-Ann Allergy 17:9-18, 1959.
7. Pressman AH: Ubuthi be-Metabolic kanye nobuhlungu be-neuromuscular, ukuphazamiseka kwamalunga, kanye ne-fibromyalgia, J Am Chiropr Assoc Septhemba:77-78, 1993.
8. Gantz NM, Holmes GP: Ukwelashwa kweziguli ezine-chronic fatigue syndrome, Izidakamizwa 36(6):855-862, 1989.
9. I-Great Smokies Diagnostic Laboratory: 63 Zillicoa St, Ashville, NC 28801, 1-704-253-0621, www.gsdl.com.
10. I-HealthComm International, Inc., Isikhungo Sokucwaninga Ngemithi Esisebenzayo, PO Box 1729, Gig Harbor, WA 98335, 1-800-843- 9660, www.healthcomm.com.
11. Metagenics, Inc., 971 Calle Negocio, San Clemente, CA 92673, 1-800-692-9400.

Vakashela Umtholampilo Wethu Namuhla!